Our Team

Program Manager

Steven Carcone, BSc MSc

With over 20 years of research experience at UHN, I currently serve as the Program Manager for the N2BL. I facilitate multi-institutional, national, and international collaborations, coordinate the development of innovative research initiatives, and lead highly effective project teams.

My responsibilities span comprehensive oversight of N2BL’s research program budgets, strategic planning, and operational excellence. Additionally, I support Dr. Valiante in key scientific activities and proudly represent our lab externally, liaising with funding agencies, stakeholders, and collaborators across national and international platforms.

Scientific Leads

Dr. Homeira Moradi, PhD

Scientific Associate, Wet lab

I’ve been a senior neuroscientist for 11 years, working with Dr. Valiante’s team to study how neuronal biophysical diversity changes in epilepsy.

At the Neuron to Brain Lab, I lead projects using brain tissue from epilepsy patients to investigate how declining neuronal biophysical diversity contributes to the condition. My research integrates electrical recordings of human cortical cells with computational models to advance our understanding of epilepsy.

I also collaborate with scientists worldwide to apply cutting-edge technology to this work. Over the years, I’ve helped build one of the largest databases of human brain electrophysiology, working with experts across disciplines to improve epilepsy research and treatment.

Dr. Ivan Skelin, MD PhD

Scientific Associate, iEEG

I am a Scientific Associate at the Neuron2Brain Lab, recording the human intracranial EEG (iEEG), single unit activity, to understand the brain dynamics underlying cognitive functioning. The other arm of my work consists of using deep brain stimulation (DBS) to modulate the brain activity in search for optimal targets for chronic stimulation in patients with various treatment-resistant pathologies (chronic pain, substance use disorder, etc.).

Research Staff

Dr. Liang Zhang, PhD

Scientific Associate

Dr. Zhang’s research has focused on uncovering the mechanisms and developing treatment strategies for epileptic seizures using rodent models. He established a clinically relevant chronic seizure-monitoring system in which mice experience spontaneous recurrent seizures that closely mimic those in human patients. This work has provided critical insights into seizure genesis, memory impairment, and abnormal brain activity. Additionally, his studies have explored the effects of deep brain stimulation (DBS) on seizure control using a novel stimulation approach. At N2BL, Dr. Zhang joins us as a lead scientist in human tissue cell reporting.

Dr. Nat Shampur, BSc

Research Analyst

I’m Nat Shampur. I work as a Research Analyst at N2Bl. Presently, I am curating the sEEG data, which is being used to train the AI model to predict seizure onset, in epileptic patients. The aim is to develop an AI/GPT model that will train seizure predicting micro-chips.

Chaitra Sarathy, PhD

Bioinformatics/Data Science Specialist

André Cornejo Marín, MASc

Research Associate

I’m André, a Research Associate at N2BL. I specialize in electrical stimulation. My research focuses on how electrical stimulation—specifically, a protocol known as Theta Burst Stimulation—can effectively alter the connectivity of the brain. Through this work, I aim to contribute to the understanding of how stimulation can modulate the intrinsic dynamics of the brain, and further aid in the development of successful treatments based on neuromodulation.

Frank Mazza, BSc MS PhD

Research Clerk

I’m an MD candidate with a near decade of experience improving depression diagnosis and treatment using innovative technology such as detailed computational models of human brain (neural spiking, LFP, EEG), repetitive transcranial magnetic stimulation (rTMS), and deep learning.

Andrew Yang, BHSc MA

Research Associate I

Mayra Santos Da Silva

Research Technician

I’m Mayra! I’m a research technician at N2BL. I specialize in inducing seizures and recording them through multi-electrode arrays . My research focuses on Epilepsy and how seizure initiates and propagates in the brain. Through this work, I get a better insight into the mechanism of seizure initiation and propagation.

Sophie Veri, BSc MSc

Research Analyst

I’m Sophie, a Research Analyst at N2BL. I am coordinating a combined fMRI-EEG study while also helping out the N2BL’s ongoing intracranial studies on epilepsy patients, and an upcoming study on deep brain stimulation to treat epilepsy.

Isabelle Keegan, BSc

Project Coordinator & Finance Manager

My name is Isabelle, and I am a Project Coordinator in the Neuron to Brain Lab. My main focus is managing Dr. Valiante’s MUSIC project, a collaborative initiative with international and local investigators dedicated to exploring the influence of music on brain health and Parkinson’s disease. In addition to overseeing this project, I also manage the lab’s finances, ensuring smooth operations and funding allocation.

Administrative Support

Caitlin Ragell, HBSc

Research Coordinator

I’m Caitlin, a Research Coordinator at N2BL. I help keep everything running smoothly behind the scenes! From managing schedules and communications to supporting research projects, I ensure that teams stay organized and on track.

Olga Dvorkin

Medical Administrative Assistant

I am a clinical administrative assistant for Dr. Valiante, supporting patient care and coordinating essential medical operations. As a passionate advocate for patients, I am dedicated to providing unwavering support and crucial information throughout their surgical journey. My mission is to empower individuals with epilepsy and their families by offering a guiding hand through the complexities of the surgical process. By sharing knowledge, fostering understanding, and ensuring a compassionate support system, I strive to make their journey more manageable and less daunting.

Students

Thomas Biba,
MA

Psychology PhD Candidate

I am a PhD student co-supervised by Dr. Taufik Valiante and Dr. Katherine Duncan at the University of Toronto. My research reveals how memory formation fluctuates on sub-second timescales, along with electrical and neuronal activity in hippocampus, recorded with intra-cranial EEG. In addition, I investigate the role of hippocampus in oculomotor guidance using deep brain stimulation. Broadly speaking, I am interested in characterizing how hippocampus coordinates shifts between perceptual and mnemonic processing, facilitating predictive operations that undergird broader cognition.

Dr. Rena Far,
BHSc MD

BME PhD Candidate

I’m Rena, a PhD student in Biomedical Engineering at UofT. I completed my MD at the University of Calgary and I am currently pursuing the research portion of my neurosurgery residency here at N2BL. My research focuses on understanding how music affects brain activity. Through this work, I hope to shed new light on how music may be used to help those with neurological conditions, such as to reduce seizure frequency in epilepsy patients and to improve motor coordination in those with Parkinson’s disease.

Noah Xiao, BEng

BME PhD Candidate

I’m Noah, a graduate student at the Institute of Biomedical Engineering, University of Toronto. I specialize in computational neuroscience. My research focuses on spatial/temporal code in the human brain. Through this work, I learn advanced neuro-technology, and data analysis.

Laura Kondrataviciute, MEng

BME PhD Candidate

I’m Laura, a PhD student at the Institute of Biomedical Engineering and joined program with Max Planck Institute, University of Toronto. I specialize in preclinical models of Parkinson’s disease and in-vivo electrophysiology. My research focuses on how alpha-synuclein overexpression in midbrain dopaminergic neurons affects basal ganglia circuit. Through this work, I try to understand the pathophysiology of Parkinson’s disease.

Yvonne Yang,
BEng

BME Masters Candidate

My name is Yvonne, and I’m a first-year MASc student at the Institute of Biomedical Engineering, University of Toronto. My background is in computer engineering. I enjoy applying different mathematical and computational tools to gain deeper understanding of the human brain. Currently, I’m building detailed models of single neurons, so we can predict its behaviour when different ionic currents (on the scale of pico-amps) cross the membrane!

Vijithan Mangaleswaran, BEng

BME Masters Candidate

I’m Vijithan, a master’s student at the Institute of Biomedical Engineering, University of Toronto. In the Neuron to Brain Lab, I specialize in studying neural population activity using microelectrode arrays (MEAs). My research focuses on how varying stimulation parameters influence neural plasticity, aiming to uncover mechanisms that shape network dynamics. Through this work, I explore advanced stimulation strategies to better understand and modulate neural activity.

Jana Ali

Behavioural Neuroscience Specialist Candidate